Used in research to measure soluble Klotho protein levels in biological samples such as serum, plasma, and cell culture supernatants. Enables scientists to study Klotho's role in aging, kidney function, cardiovascular health, and metabolic regulation. Commonly applied in studies related to chronic diseases including diabetes, osteoporosis, and neurodegenerative disorders. Supports investigation into biomarkers for age-related conditions and evaluation of therapeutic interventions targeting Klotho pathways.