Human O-6-methylguanine DNA methyltransferase (MGMT) ELISA Research Kit,
Reagent
Code: #251437
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Used in research settings to quantify levels of O-6-methylguanine DNA methyltransferase (MGMT) protein in human biological samples. This kit supports studies on DNA repair mechanisms, particularly in the context of cancer research, where MGMT expression is linked to resistance to alkylating chemotherapeutic agents like temozolomide. By measuring MGMT protein concentration, researchers can assess tumor repair capacity, evaluate potential response to chemotherapy, and explore epigenetic silencing of the MGMT gene. The assay is commonly applied in neuro-oncology, especially in glioblastoma research, to support biomarker development and personalized treatment strategies. Suitable for use with cell lysates, tissue homogenates, and other sample types in academic, clinical, and pharmaceutical laboratories.
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