Used in RNA structure analysis and sequencing due to its specificity for guanosine residues, cleaving the 3'-O-P bond of guanylic acid in RNA. Commonly employed in footprinting assays to study RNA-protein interactions and to generate RNA fragments for mapping secondary structures. Also utilized in the removal of RNA from DNA preparations and in studies requiring precise RNA degradation. Its high purity and stability in lyophilized form make it suitable for sensitive molecular biology applications.