Used in biomedical research to measure levels of tartrate-resistant acid phosphatase 5b (TRAP5b), a biomarker for osteoclast activity. Helps assess bone resorption and turnover in studies related to osteoporosis, metabolic bone diseases, and bone metastasis. Commonly applied in preclinical studies, clinical trials, and laboratory research involving bone metabolism. Enables quantification of TRAP5b in serum or plasma samples, supporting evaluation of therapeutic responses to anti-resorptive treatments like bisphosphonates or denosumab.