huTREM1-HEK293 is used in biomedical research to study the role of the Triggering Receptor Expressed on Myeloid cells-1 (TREM1) in inflammation and immune responses. It serves as a cellular model expressing human TREM1, enabling scientists to investigate signaling pathways involved in infectious diseases, sepsis, and inflammatory disorders. This system supports the development and testing of therapeutic agents such as antibodies or small molecules targeting TREM1 to modulate excessive inflammation. It is also employed in assay development for drug screening and validation of target engagement in a human-relevant cellular context.