Used in biomedical research to measure levels of YKL-40 protein in biological samples such as serum, plasma, and cell culture supernatants. Helps in studying inflammatory diseases including rheumatoid arthritis, asthma, and inflammatory bowel disease. Supports cancer research by quantifying YKL-40, which is elevated in glioblastoma, breast cancer, and lung cancer. Applied in neurological studies to assess neuroinflammation and disease progression in conditions like Alzheimer's and multiple sclerosis. Enables monitoring of disease activity and response to therapy in clinical and preclinical settings.