(S,R,S)-AHPC-PEG3-N3 (VH032-PEG3-N3)
98%
- Product Code: 106734
CAS:
1797406-80-4
| Molecular Weight: | 645.77 g./mol | Molecular Formula: | C₃₀H₄₃N₇O₇S |
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| Density: | Storage Condition: | -20°C, airtight, dry |
Product Description:
(S,R,S)-AHPC-PEG3-N3 (VH032-PEG3-N3) is primarily used in the field of targeted protein degradation, particularly in the development of PROTACs (Proteolysis Targeting Chimeras). This compound serves as a key linker molecule that connects an E3 ligase ligand to a target protein-binding moiety. Its triethylene glycol (PEG3) spacer ensures optimal distance and flexibility between the two components, enhancing the efficiency of the ternary complex formation. The azide (N3) group allows for further functionalization through click chemistry, enabling precise conjugation with various target-specific ligands. This makes it a valuable tool in drug discovery and chemical biology for studying protein function, identifying new therapeutic targets, and developing novel degradation-based therapies for diseases such as cancer and neurodegenerative disorders.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿54,990.00 |
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(S,R,S)-AHPC-PEG3-N3 (VH032-PEG3-N3)
(S,R,S)-AHPC-PEG3-N3 (VH032-PEG3-N3) is primarily used in the field of targeted protein degradation, particularly in the development of PROTACs (Proteolysis Targeting Chimeras). This compound serves as a key linker molecule that connects an E3 ligase ligand to a target protein-binding moiety. Its triethylene glycol (PEG3) spacer ensures optimal distance and flexibility between the two components, enhancing the efficiency of the ternary complex formation. The azide (N3) group allows for further functionalization through click chemistry, enabling precise conjugation with various target-specific ligands. This makes it a valuable tool in drug discovery and chemical biology for studying protein function, identifying new therapeutic targets, and developing novel degradation-based therapies for diseases such as cancer and neurodegenerative disorders.
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