2,4-Thiazolidinedione
99%
- Product Code: 115381
Alias:
2,4-Thiazolidinedione
CAS:
2295-31-0
| Molecular Weight: | 117.13 g./mol | Molecular Formula: | C₃H₃NO₂S |
|---|---|---|---|
| EC Number: | 218-941-2 | MDL Number: | MFCD00005478 |
| Melting Point: | 125-127 °C(lit.) | Boiling Point: | 178-179 °C (19 mmHg) |
| Density: | Storage Condition: | room temperature |
Product Description:
2,4-Thiazolidinedione is primarily used in the development of pharmaceuticals, particularly in the treatment of type 2 diabetes. It serves as a core structure in the synthesis of thiazolidinedione-class drugs, such as pioglitazone and rosiglitazone, which are insulin sensitizers. These drugs work by activating peroxisome proliferator-activated receptors (PPARs), specifically PPAR-gamma, to improve insulin sensitivity in adipose tissue, muscle, and the liver. This helps regulate blood sugar levels in diabetic patients. Additionally, research has explored its potential in addressing metabolic syndrome, inflammation, and certain cancers due to its PPAR-gamma modulating properties. However, its use is often limited due to associated side effects, such as weight gain and cardiovascular risks.
Product Specification:
| Test | Specification |
|---|---|
| Melting Point | 123-128 |
| Purity (HPLC) | 99-100 |
| Appearance | White To Light Yellow Powder Or Crystals |
| Infrared Spectrum | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 25.000 | 10-20 days | ฿300.00 |
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| 100.000 | 10-20 days | ฿530.00 |
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| 500.000 | 10-20 days | ฿1,990.00 |
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| 2500.000 | 10-20 days | ฿9,350.00 |
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2,4-Thiazolidinedione
2,4-Thiazolidinedione is primarily used in the development of pharmaceuticals, particularly in the treatment of type 2 diabetes. It serves as a core structure in the synthesis of thiazolidinedione-class drugs, such as pioglitazone and rosiglitazone, which are insulin sensitizers. These drugs work by activating peroxisome proliferator-activated receptors (PPARs), specifically PPAR-gamma, to improve insulin sensitivity in adipose tissue, muscle, and the liver. This helps regulate blood sugar levels in diabetic patients. Additionally, research has explored its potential in addressing metabolic syndrome, inflammation, and certain cancers due to its PPAR-gamma modulating properties. However, its use is often limited due to associated side effects, such as weight gain and cardiovascular risks.
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