Sarecycline hydrochloride is primarily used as an antibiotic to treat moderate to severe acne vulgaris. It works by inhibiting bacterial protein synthesis, specifically targeting the bacteria responsible for acne, such as Cutibacterium acnes. This medication is often prescribed when other treatments have not been effective. It is typically administered orally in tablet form and is designed to minimize the disruption of the gut microbiome compared to other tetracycline-class antibiotics. Patients are usually advised to take it once daily with or without food, and it is important to complete the full course of treatment to achieve optimal results. Common side effects may include mild gastrointestinal discomfort, headaches, or photosensitivity, but it is generally well-tolerated. It is particularly favored for its targeted action and reduced risk of antibiotic resistance.