1-Iodobutane is primarily used in organic synthesis as an alkylating agent, where it introduces the butyl group into various chemical compounds. It is commonly employed in the preparation of pharmaceuticals, agrochemicals, and other organic intermediates. In research laboratories, it serves as a reagent for nucleophilic substitution reactions, particularly in the formation of carbon-carbon bonds. Additionally, it is utilized in the synthesis of organometallic compounds, such as Grignard reagents, which are essential in creating complex organic molecules. Its role in the production of surfactants and lubricant additives also highlights its industrial significance.