1-Boc-5-fluoroindole-2-boronic Acid
98%
Reagent
Code: #123873
CAS Number
352359-23-0
blur_circular Chemical Specifications
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Molecular Information
Weight
279.07 g/mol
Formula
C₁₃H₁₅BFNO₄
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Registry Numbers
MDL Number
MFCD04114581
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Physical Properties
Melting Point
130-140 °C
Boiling Point
446.5±55.0 °C(Predicted)
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Storage & Handling
Density
1.24±0.1 g/cm3(Predicted)
Storage
-20°C, inert gas
description Product Description
Used primarily in organic synthesis, this compound serves as a key intermediate in the preparation of more complex molecules, particularly in pharmaceutical research. It is often employed in Suzuki-Miyaura cross-coupling reactions, a widely utilized method for forming carbon-carbon bonds, which is crucial in the development of drug candidates. Its Boc (tert-butoxycarbonyl) protecting group ensures stability during reactions, while the boronic acid moiety facilitates coupling with various aryl or vinyl halides. This makes it valuable in constructing indole-based compounds, which are prevalent in many bioactive molecules and drugs targeting neurological disorders, cancer, and other diseases. Additionally, its fluorine substituent can enhance the metabolic stability and binding affinity of the resulting compounds.
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1-Boc-5-fluoroindole-2-boronic Acid
Used primarily in organic synthesis, this compound serves as a key intermediate in the preparation of more complex molecules, particularly in pharmaceutical research. It is often employed in Suzuki-Miyaura cross-coupling reactions, a widely utilized method for forming carbon-carbon bonds, which is crucial in the development of drug candidates. Its Boc (tert-butoxycarbonyl) protecting group ensures stability during reactions, while the boronic acid moiety facilitates coupling with various aryl or vinyl halides. This makes it valuable in constructing indole-based compounds, which are prevalent in many bioactive molecules and drugs targeting neurological disorders, cancer, and other diseases. Additionally, its fluorine substituent can enhance the metabolic stability and binding affinity of the resulting compounds.
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