1-Boc-5-fluoroindole-2-boronic Acid

98%

Reagent Code: #123873
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CAS Number 352359-23-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 279.07 g/mol
Formula C₁₃H₁₅BFNO₄
badge Registry Numbers
MDL Number MFCD04114581
thermostat Physical Properties
Melting Point 130-140 °C
Boiling Point 446.5±55.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.24±0.1 g/cm3(Predicted)
Storage -20°C, inert gas

description Product Description

Used primarily in organic synthesis, this compound serves as a key intermediate in the preparation of more complex molecules, particularly in pharmaceutical research. It is often employed in Suzuki-Miyaura cross-coupling reactions, a widely utilized method for forming carbon-carbon bonds, which is crucial in the development of drug candidates. Its Boc (tert-butoxycarbonyl) protecting group ensures stability during reactions, while the boronic acid moiety facilitates coupling with various aryl or vinyl halides. This makes it valuable in constructing indole-based compounds, which are prevalent in many bioactive molecules and drugs targeting neurological disorders, cancer, and other diseases. Additionally, its fluorine substituent can enhance the metabolic stability and binding affinity of the resulting compounds.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿4,563.00
inventory 5g
10-20 days ฿15,804.00
inventory 250mg
10-20 days ฿1,719.00
1-Boc-5-fluoroindole-2-boronic Acid
Used primarily in organic synthesis, this compound serves as a key intermediate in the preparation of more complex molecules, particularly in pharmaceutical research. It is often employed in Suzuki-Miyaura cross-coupling reactions, a widely utilized method for forming carbon-carbon bonds, which is crucial in the development of drug candidates. Its Boc (tert-butoxycarbonyl) protecting group ensures stability during reactions, while the boronic acid moiety facilitates coupling with various aryl or vinyl halides. This makes it valuable in constructing indole-based compounds, which are prevalent in many bioactive molecules and drugs targeting neurological disorders, cancer, and other diseases. Additionally, its fluorine substituent can enhance the metabolic stability and binding affinity of the resulting compounds.
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