1-Boc-5-fluoroindole-2-boronic Acid
98%
- Product Code: 123873
CAS:
352359-23-0
| Molecular Weight: | 279.07 g./mol | Molecular Formula: | C₁₃H₁₅BFNO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD04114581 | |
| Melting Point: | 130-140 °C | Boiling Point: | 446.5±55.0 °C(Predicted) |
| Density: | 1.24±0.1 g/cm3(Predicted) | Storage Condition: | -20°C, inert gas |
Product Description:
Used primarily in organic synthesis, this compound serves as a key intermediate in the preparation of more complex molecules, particularly in pharmaceutical research. It is often employed in Suzuki-Miyaura cross-coupling reactions, a widely utilized method for forming carbon-carbon bonds, which is crucial in the development of drug candidates. Its Boc (tert-butoxycarbonyl) protecting group ensures stability during reactions, while the boronic acid moiety facilitates coupling with various aryl or vinyl halides. This makes it valuable in constructing indole-based compounds, which are prevalent in many bioactive molecules and drugs targeting neurological disorders, cancer, and other diseases. Additionally, its fluorine substituent can enhance the metabolic stability and binding affinity of the resulting compounds.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | ฿1,719.00 |
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| 1.000 | 10-20 days | ฿4,563.00 |
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| 5.000 | 10-20 days | ฿15,804.00 |
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1-Boc-5-fluoroindole-2-boronic Acid
Used primarily in organic synthesis, this compound serves as a key intermediate in the preparation of more complex molecules, particularly in pharmaceutical research. It is often employed in Suzuki-Miyaura cross-coupling reactions, a widely utilized method for forming carbon-carbon bonds, which is crucial in the development of drug candidates. Its Boc (tert-butoxycarbonyl) protecting group ensures stability during reactions, while the boronic acid moiety facilitates coupling with various aryl or vinyl halides. This makes it valuable in constructing indole-based compounds, which are prevalent in many bioactive molecules and drugs targeting neurological disorders, cancer, and other diseases. Additionally, its fluorine substituent can enhance the metabolic stability and binding affinity of the resulting compounds.
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