Thalidomide-O-amido-PEG-C2-NH2 hydrochloride
≥95%
Reagent
Code: #125112
CAS Number
2204226-02-6
blur_circular Chemical Specifications
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Molecular Information
Weight
454.86 g/mol
Formula
C₁₉H₂₃ClN₄O₇
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Registry Numbers
MDL Number
MFCD32063469
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Storage & Handling
Storage
2-8°C, dry, sealed
description Product Description
Used primarily in targeted drug delivery systems, this compound acts as a linker to conjugate therapeutic agents, such as thalidomide derivatives, to polyethylene glycol (PEG) chains. The PEGylation enhances the solubility, stability, and bioavailability of the drug, while the thalidomide moiety can be utilized for its immunomodulatory and anti-angiogenic properties. The amine group in the structure allows for further functionalization, enabling attachment to specific targeting molecules or nanoparticles. This makes it valuable in developing treatments for cancers, inflammatory diseases, and other conditions where precise drug delivery is critical. Its application is particularly relevant in designing prodrugs or antibody-drug conjugates for improved therapeutic efficacy and reduced side effects.
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Thalidomide-O-amido-PEG-C2-NH2 hydrochloride
Used primarily in targeted drug delivery systems, this compound acts as a linker to conjugate therapeutic agents, such as thalidomide derivatives, to polyethylene glycol (PEG) chains. The PEGylation enhances the solubility, stability, and bioavailability of the drug, while the thalidomide moiety can be utilized for its immunomodulatory and anti-angiogenic properties. The amine group in the structure allows for further functionalization, enabling attachment to specific targeting molecules or nanoparticles. This makes it valuable in developing treatments for cancers, inflammatory diseases, and other conditions where precise drug delivery is critical. Its application is particularly relevant in designing prodrugs or antibody-drug conjugates for improved therapeutic efficacy and reduced side effects.
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