3-Chloro-5-pyrrolidinophenylboronic acid, pinacol ester

96%

Reagent Code: #131304
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CAS Number 2096331-84-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 307.62 g/mol
Formula C₁₆H₂₃BClNO₂
badge Registry Numbers
MDL Number MFCD18783182
thermostat Physical Properties
Boiling Point 437.7±40.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.14±0.1 g/cm3(Predicted)
Storage 2-8°C, sealed, dry

description Product Description

Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its boronic ester functionality enables efficient Suzuki-Miyaura cross-coupling reactions, allowing for the construction of complex biaryl structures in drug molecules. The presence of the pyrrolidinyl group enhances solubility and binding selectivity, making it valuable in optimizing drug potency and pharmacokinetic properties. Commonly employed in medicinal chemistry research for lead optimization and library synthesis.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days $99.71
inventory 250mg
10-20 days $157.30
3-Chloro-5-pyrrolidinophenylboronic acid, pinacol ester
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its boronic ester functionality enables efficient Suzuki-Miyaura cross-coupling reactions, allowing for the construction of complex biaryl structures in drug molecules. The presence of the pyrrolidinyl group enhances solubility and binding selectivity, making it valuable in optimizing drug potency and pharmacokinetic properties. Commonly employed in medicinal chemistry research for lead optimization and library synthesis.
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