3-Chloro-5-pyrrolidinophenylboronic acid, pinacol ester
96%
Reagent
Code: #131304
CAS Number
2096331-84-7
blur_circular Chemical Specifications
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Molecular Information
Weight
307.62 g/mol
Formula
C₁₆H₂₃BClNO₂
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Registry Numbers
MDL Number
MFCD18783182
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Physical Properties
Boiling Point
437.7±40.0 °C(Predicted)
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Storage & Handling
Density
1.14±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its boronic ester functionality enables efficient Suzuki-Miyaura cross-coupling reactions, allowing for the construction of complex biaryl structures in drug molecules. The presence of the pyrrolidinyl group enhances solubility and binding selectivity, making it valuable in optimizing drug potency and pharmacokinetic properties. Commonly employed in medicinal chemistry research for lead optimization and library synthesis.
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3-Chloro-5-pyrrolidinophenylboronic acid, pinacol ester
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its boronic ester functionality enables efficient Suzuki-Miyaura cross-coupling reactions, allowing for the construction of complex biaryl structures in drug molecules. The presence of the pyrrolidinyl group enhances solubility and binding selectivity, making it valuable in optimizing drug potency and pharmacokinetic properties. Commonly employed in medicinal chemistry research for lead optimization and library synthesis.
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