Methyl 2-((tert-butoxycarbonyl)amino)-2-(4,4-difluorocyclohexyl)acetate
98%
Reagent
Code: #131675
CAS Number
2270904-94-2
blur_circular Chemical Specifications
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Molecular Information
Weight
307.33 g/mol
Formula
C₁₄H₂₃F₂NO₄
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Registry Numbers
MDL Number
MFCD04115609
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Physical Properties
Boiling Point
375.6±22.0 °C(Predicted)
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Storage & Handling
Density
1.15±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of fluorinated analogs of bioactive molecules. Its structure supports the introduction of a difluorocyclohexyl group, which can enhance metabolic stability and membrane permeability in drug candidates. Commonly employed in medicinal chemistry for constructing peptidomimetics and enzyme inhibitors where steric and electronic effects of fluorine play a key role. The Boc-protected amine allows for selective deprotection and further coupling in multi-step organic syntheses, making it valuable in solid-phase and solution-phase peptide synthesis.
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Methyl 2-((tert-butoxycarbonyl)amino)-2-(4,4-difluorocyclohexyl)acetate
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of fluorinated analogs of bioactive molecules. Its structure supports the introduction of a difluorocyclohexyl group, which can enhance metabolic stability and membrane permeability in drug candidates. Commonly employed in medicinal chemistry for constructing peptidomimetics and enzyme inhibitors where steric and electronic effects of fluorine play a key role. The Boc-protected amine allows for selective deprotection and further coupling in multi-step organic syntheses, making it valuable in solid-phase and solution-phase peptide synthesis.
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