(3-Methyl-4-(pyrrolidin-1-ylsulfonyl)phenyl)boronic acid
98%
Reagent
Code: #131683
CAS Number
2377608-95-0
blur_circular Chemical Specifications
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Molecular Information
Weight
269.12 g/mol
Formula
C₁₁H₁₆BNO₄S
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Registry Numbers
MDL Number
MFCD31726401
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Physical Properties
Boiling Point
478.9±55.0 °C(Predicted)
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Storage & Handling
Density
1.37±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for targeted cancer therapies. Its boronic acid functionality enables Suzuki-Miyaura cross-coupling reactions, facilitating the construction of complex biaryl structures in drug molecules. Commonly employed in medicinal chemistry for optimizing lead compounds due to its ability to enhance binding affinity and metabolic stability. Also utilized in the preparation of proteolysis-targeting chimeras (PROTACs) and other bifunctional molecules where precise molecular assembly is critical.
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(3-Methyl-4-(pyrrolidin-1-ylsulfonyl)phenyl)boronic acid
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for targeted cancer therapies. Its boronic acid functionality enables Suzuki-Miyaura cross-coupling reactions, facilitating the construction of complex biaryl structures in drug molecules. Commonly employed in medicinal chemistry for optimizing lead compounds due to its ability to enhance binding affinity and metabolic stability. Also utilized in the preparation of proteolysis-targeting chimeras (PROTACs) and other bifunctional molecules where precise molecular assembly is critical.
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