5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isothiazole
98%
Reagent
Code: #131872
CAS Number
1045809-78-6
blur_circular Chemical Specifications
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Molecular Information
Weight
211.09 g/mol
Formula
C₉H₁₄BNO₂S
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Registry Numbers
MDL Number
MFCD08061126
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Physical Properties
Boiling Point
234.4±22.0 °C(Predicted)
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Storage & Handling
Density
1.12±0.1 g/cm3(Predicted)
Storage
-20°C, Sealed, Dry
description Product Description
Used primarily in cross-coupling reactions, this compound serves as a key building block in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient Suzuki-Miyaura coupling, allowing for the formation of carbon-carbon bonds with aryl or heteroaryl halides. This makes it valuable in medicinal chemistry for constructing biaryl systems found in bioactive molecules. It is also employed in the development of functional materials, including organic semiconductors and ligands for catalysts, due to the stability and reactivity of the isothiazole ring combined with the versatility of the boronate functionality.
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5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isothiazole
Used primarily in cross-coupling reactions, this compound serves as a key building block in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient Suzuki-Miyaura coupling, allowing for the formation of carbon-carbon bonds with aryl or heteroaryl halides. This makes it valuable in medicinal chemistry for constructing biaryl systems found in bioactive molecules. It is also employed in the development of functional materials, including organic semiconductors and ligands for catalysts, due to the stability and reactivity of the isothiazole ring combined with the versatility of the boronate functionality.
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