Acelarin

10mM in DMSO

Reagent Code: #134037
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CAS Number 840506-29-8

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Weight 580.47 g/mol
Formula C₂₅H₂₇F₂N₄O₈P
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in the treatment of various solid tumors, particularly in advanced or metastatic cancers such as pancreatic, ovarian, and non-small cell lung cancer. It functions as a prodrug of gemcitabine, designed to overcome resistance mechanisms that limit the effectiveness of gemcitabine in some patients. By improving cellular uptake and retention, it enhances cytotoxic activity against tumor cells. It is under clinical investigation for its potential to provide better therapeutic outcomes in patients who have failed prior gemcitabine-based therapies. Its application is primarily in oncology, especially in settings where conventional nucleoside analogs show limited efficacy.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿12,300.00
Acelarin
Used in the treatment of various solid tumors, particularly in advanced or metastatic cancers such as pancreatic, ovarian, and non-small cell lung cancer. It functions as a prodrug of gemcitabine, designed to overcome resistance mechanisms that limit the effectiveness of gemcitabine in some patients. By improving cellular uptake and retention, it enhances cytotoxic activity against tumor cells. It is under clinical investigation for its potential to provide better therapeutic outcomes in patients who have failed prior gemcitabine-based therapies. Its application is primarily in oncology, especially in settings where conventional nucleoside analogs show limited efficacy.
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