ARN-509

10mM in DMSO

Reagent Code: #134058
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CAS Number 956104-40-8

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Weight 477.43 g/mol
Formula C₂₁H₁₅F₄N₅O₂S
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in the treatment of prostate cancer, particularly metastatic castration-resistant prostate cancer (mCRPC). It functions as an androgen receptor inhibitor, blocking the activity of androgens like testosterone that can promote tumor growth. By binding to the androgen receptor, it prevents receptor translocation to the cell nucleus and inhibits binding to DNA, thereby reducing cancer cell proliferation. It is administered orally and has shown efficacy in delaying disease progression and improving survival outcomes in clinical trials. Often used when other treatments have failed or are no longer effective.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿11,630.00
ARN-509
Used in the treatment of prostate cancer, particularly metastatic castration-resistant prostate cancer (mCRPC). It functions as an androgen receptor inhibitor, blocking the activity of androgens like testosterone that can promote tumor growth. By binding to the androgen receptor, it prevents receptor translocation to the cell nucleus and inhibits binding to DNA, thereby reducing cancer cell proliferation. It is administered orally and has shown efficacy in delaying disease progression and improving survival outcomes in clinical trials. Often used when other treatments have failed or are no longer effective.
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