AMG9810 is primarily used in scientific research to study pain pathways and thermoregulation. It acts as a potent antagonist of the TRPV1 receptor, which is involved in the perception of heat and pain. By blocking this receptor, AMG9810 helps researchers investigate the role of TRPV1 in inflammatory and neuropathic pain conditions. It is also utilized in preclinical studies to evaluate potential therapeutic strategies for pain management, especially in models where heat hypersensitivity is a factor. Its selectivity makes it a valuable tool for understanding sensory neuron function without affecting other related ion channels.