Used in the treatment of inflammatory and autoimmune diseases, particularly rheumatoid arthritis. Targets and neutralizes GM-CSF (granulocyte-macrophage colony-stimulating factor), a key cytokine involved in the activation and proliferation of macrophages and other immune cells that drive inflammation and joint damage. By inhibiting GM-CSF, it helps reduce disease activity, slow progression of joint destruction, and improve physical function in patients. Also under investigation for conditions like osteoarthritis and diffuse cutaneous systemic sclerosis due to its role in modulating immune-driven tissue inflammation.