Anti-HGFR / c-Met Reference Antibody (onartuzumab)
- Product Code: 140143
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Product Description:
Used in targeted cancer therapy, particularly for tumors exhibiting dysregulated c-MET signaling pathway activity. Binds specifically to the extracellular domain of the c-MET receptor, blocking hepatocyte growth factor (HGF) interaction and inhibiting downstream signaling involved in tumor growth, invasion, and metastasis. Investigated in clinical trials for non-small cell lung cancer, gastric cancer, and other solid tumors, often in combination with other targeted agents or chemotherapy. Designed for intravenous administration as a humanized monoclonal antibody to minimize immunogenicity while enhancing therapeutic efficacy.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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10-20 days | €131.61 |
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Anti-HGFR / c-Met Reference Antibody (onartuzumab)
Used in targeted cancer therapy, particularly for tumors exhibiting dysregulated c-MET signaling pathway activity. Binds specifically to the extracellular domain of the c-MET receptor, blocking hepatocyte growth factor (HGF) interaction and inhibiting downstream signaling involved in tumor growth, invasion, and metastasis. Investigated in clinical trials for non-small cell lung cancer, gastric cancer, and other solid tumors, often in combination with other targeted agents or chemotherapy. Designed for intravenous administration as a humanized monoclonal antibody to minimize immunogenicity while enhancing therapeutic efficacy.
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