Used in research and diagnostic applications to detect and quantify HTRA1 protein expression in biological samples. Plays a key role in studies related to age-related macular degeneration (AMD), as HTRA1 is implicated in the pathogenesis of the disease. Enables immunohistochemistry, Western blotting, and ELISA assays to investigate HTRA1's involvement in cellular stress, apoptosis, and extracellular matrix regulation. Also supports therapeutic development by serving as a reference standard in antibody validation and assay calibration.