Used in research and therapeutic development for its role in targeting the Klotho beta protein, which is involved in metabolic regulation and cellular aging processes. This antibody serves as a reference tool in immunoassays to detect and quantify Klotho beta expression in biological samples. It supports studies on diseases linked to aging, chronic kidney disease, and metabolic disorders such as diabetes. Due to its high specificity, it enables accurate measurement of target engagement in preclinical and clinical studies. It is also utilized in the development and validation of companion diagnostics for therapies targeting the FGF23-Klotho signaling pathway.