7-(Benzyloxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
98%
Reagent
Code: #140854
CAS Number
1197196-47-6
blur_circular Chemical Specifications
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Molecular Information
Weight
490.64 g/mol
Formula
C₂₈H₃₈N₆O₂
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Registry Numbers
MDL Number
MFCD27963848
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Physical Properties
Boiling Point
662.3±65.0 °C(Predicted)
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Storage & Handling
Density
1.188±0.06 g/cm3(Predicted)
Storage
2-8°C, sealed, dry, light-proof
description Product Description
Used as a key intermediate in the synthesis of selective kinase inhibitors, particularly in the development of anticancer agents targeting EGFR (epidermal growth factor receptor) and HER2 pathways. Its structure enables strong binding affinity and selectivity, making it valuable in pharmaceutical research for treating non-small cell lung cancer and other solid tumors. Also employed in structure-activity relationship (SAR) studies to optimize potency, solubility, and metabolic stability in drug candidates.
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7-(Benzyloxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
Used as a key intermediate in the synthesis of selective kinase inhibitors, particularly in the development of anticancer agents targeting EGFR (epidermal growth factor receptor) and HER2 pathways. Its structure enables strong binding affinity and selectivity, making it valuable in pharmaceutical research for treating non-small cell lung cancer and other solid tumors. Also employed in structure-activity relationship (SAR) studies to optimize potency, solubility, and metabolic stability in drug candidates.
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