Used as a polar aprotic solvent in organic synthesis, particularly in pharmaceutical manufacturing where high solvency and thermal stability are required. It facilitates reactions such as nucleophilic substitutions and coupling reactions due to its ability to dissolve a wide range of organic and inorganic compounds. Also employed in the formulation of specialty coatings and electronic materials because of its low volatility and excellent film-forming properties. Its structural compatibility with heterocyclic systems makes it useful as an intermediate in the development of active pharmaceutical ingredients.