Boc-HomoSer(Bzl)-OH

98%

Reagent Code: #145818
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CAS Number 59408-74-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 309.36 g/mol
Formula C₁₆H₂₃NO₅
badge Registry Numbers
MDL Number MFCD00270497
thermostat Physical Properties
Boiling Point 480.5°C
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used in peptide synthesis as a protected amino acid building block. The Boc group protects the amine functionality, while the benzyl (Bzl) group protects the side chain hydroxyl of homoserine. This allows selective coupling at the carboxylic acid during solid-phase or solution-phase peptide assembly. After incorporation into the peptide chain, the Boc group can be removed under mild acidic conditions without affecting the benzyl protection. The benzyl group is later removed in the final deprotection step, typically via hydrogenolysis or strong acid like HF, to yield the free hydroxyl group in the target peptide. Commonly used in the synthesis of complex bioactive peptides where side chain protection is required.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿973.50
inventory 5g
10-20 days ฿3,866.50
inventory 250mg
10-20 days ฿275.00
Boc-HomoSer(Bzl)-OH
Used in peptide synthesis as a protected amino acid building block. The Boc group protects the amine functionality, while the benzyl (Bzl) group protects the side chain hydroxyl of homoserine. This allows selective coupling at the carboxylic acid during solid-phase or solution-phase peptide assembly. After incorporation into the peptide chain, the Boc group can be removed under mild acidic conditions without affecting the benzyl protection. The benzyl group is later removed in the final deprotection step, typically via hydrogenolysis or strong acid like HF, to yield the free hydroxyl group in the target peptide. Commonly used in the synthesis of complex bioactive peptides where side chain protection is required.
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