5-(di-tert-Butylphosphino)-1',3',5'-triphenyl-1'H-1,4'-bipyrazole
98%
Reagent
Code: #148957
CAS Number
894086-00-1
blur_circular Chemical Specifications
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Molecular Information
Weight
506.6209 g/mol
Formula
C₃₂H₃₅N₄P
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Registry Numbers
MDL Number
MFCD09038440
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Physical Properties
Melting Point
169-173 °C
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a specialized ligand in transition metal catalysis, particularly in palladium-catalyzed cross-coupling reactions. Its sterically bulky phosphine group enhances catalyst stability and influences selectivity, making it effective in Suzuki–Miyaura and Buchwald–Hartwig aminations. The electron-rich nature of the phosphine moiety promotes oxidative addition steps, improving reaction efficiency under mild conditions. Commonly employed in pharmaceutical synthesis and materials science where high catalytic activity and functional group tolerance are required.
format_list_bulleted Product Specification
Test Parameter | Specification |
---|---|
Appearance | White to pale yellow powder or crystals |
Purity (%) | 97.5-100 |
Infrared Spectrum | Conforms to Structure |
NMR | Conforms to Structure |
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5-(di-tert-Butylphosphino)-1',3',5'-triphenyl-1'H-1,4'-bipyrazole
Used as a specialized ligand in transition metal catalysis, particularly in palladium-catalyzed cross-coupling reactions. Its sterically bulky phosphine group enhances catalyst stability and influences selectivity, making it effective in Suzuki–Miyaura and Buchwald–Hartwig aminations. The electron-rich nature of the phosphine moiety promotes oxidative addition steps, improving reaction efficiency under mild conditions. Commonly employed in pharmaceutical synthesis and materials science where high catalytic activity and functional group tolerance are required.
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