1,7-Bis(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane
98 %
Reagent
Code: #149608
CAS Number
162148-48-3
blur_circular Chemical Specifications
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Molecular Information
Weight
400.56 g/mol
Formula
C₂₀H₄₀N₄O₄
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Registry Numbers
MDL Number
MFCD09263303
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Storage & Handling
Storage
Room temperature, dry, inert gas
description Product Description
Widely used in medical imaging and radiopharmaceuticals, this compound serves as a key chelating agent for stabilizing metal ions, especially radioactive ones like gadolinium, yttrium, and lutetium. Its primary application lies in the development of contrast agents for MRI, where it enhances image clarity by tightly binding paramagnetic metals and reducing their toxicity. Due to its high selectivity and stability, it is also employed in targeted radiotherapy, particularly in cancer treatment, where it helps deliver therapeutic isotopes directly to tumor cells. The structure allows for easy functionalization, making it suitable for conjugation with peptides, antibodies, or other targeting molecules. This enables precise delivery in diagnostic and therapeutic applications, especially in PET imaging and somatostatin receptor-targeted treatments.
format_list_bulleted Product Specification
Test Parameter | Specification |
---|---|
Appearance | White Powder |
Purity (%) | 97.5-100 |
Infrared Spectrum | Conforms to Structure |
NMR | Conforms to Structure |
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1,7-Bis(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane
Widely used in medical imaging and radiopharmaceuticals, this compound serves as a key chelating agent for stabilizing metal ions, especially radioactive ones like gadolinium, yttrium, and lutetium. Its primary application lies in the development of contrast agents for MRI, where it enhances image clarity by tightly binding paramagnetic metals and reducing their toxicity. Due to its high selectivity and stability, it is also employed in targeted radiotherapy, particularly in cancer treatment, where it helps deliver therapeutic isotopes directly to tumor cells. The structure allows for easy functionalization, making it suitable for conjugation with peptides, antibodies, or other targeting molecules. This enables precise delivery in diagnostic and therapeutic applications, especially in PET imaging and somatostatin receptor-targeted treatments.
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