tert-Butyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)carbamate
97%
Reagent
Code: #151225
CAS Number
1171897-39-4
blur_circular Chemical Specifications
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Molecular Information
Weight
320.19 g/mol
Formula
C₁₆H₂₅BN₂O₄
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Registry Numbers
MDL Number
MFCD13195277
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Physical Properties
Boiling Point
400.7±30.0 °C at 760 mmHg
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Storage & Handling
Storage
-20°C, light-proof, inert gas storage
description Product Description
Widely used in cross-coupling reactions, this compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient Suzuki-Miyaura coupling, allowing for the formation of biaryl and heteroaryl structures under mild conditions. The tert-butyl carbamate (Boc) protecting group stabilizes the amine functionality during reactions and can be easily removed later in the synthesis. This makes the compound particularly valuable in the development of nitrogen-containing drug candidates, where selective and stepwise construction of complex molecules is required. It is also employed in the preparation of functional materials and ligands for catalysis.
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tert-Butyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)carbamate
Widely used in cross-coupling reactions, this compound serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient Suzuki-Miyaura coupling, allowing for the formation of biaryl and heteroaryl structures under mild conditions. The tert-butyl carbamate (Boc) protecting group stabilizes the amine functionality during reactions and can be easily removed later in the synthesis. This makes the compound particularly valuable in the development of nitrogen-containing drug candidates, where selective and stepwise construction of complex molecules is required. It is also employed in the preparation of functional materials and ligands for catalysis.
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