3-((tert-Butyldimethylsilyl)oxy)cyclobutanone
98%
Reagent
Code: #153701
CAS Number
929913-18-8
blur_circular Chemical Specifications
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Molecular Information
Weight
200.353 g/mol
Formula
C₁₀H₂₀O₂Si
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Registry Numbers
MDL Number
MFCD23105928
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Storage & Handling
Storage
-20°C, dry
description Product Description
Used primarily as a protected hydroxyketone intermediate in organic synthesis, particularly in the construction of complex natural products and pharmaceuticals. The silyl ether group provides stability and selectivity during multi-step reactions, allowing for controlled transformations at other reactive sites. Commonly employed in stereoselective reductions, nucleophilic additions, and ring-forming reactions where protection of the alcohol functionality is required. Its cyclobutanone core serves as a strained ring system useful in ring-expansion or fragmentation strategies. Widely utilized in medicinal chemistry for the synthesis of bioactive molecules where temporary protection of polar groups is needed to improve solubility or reactivity in non-aqueous environments.
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3-((tert-Butyldimethylsilyl)oxy)cyclobutanone
Used primarily as a protected hydroxyketone intermediate in organic synthesis, particularly in the construction of complex natural products and pharmaceuticals. The silyl ether group provides stability and selectivity during multi-step reactions, allowing for controlled transformations at other reactive sites. Commonly employed in stereoselective reductions, nucleophilic additions, and ring-forming reactions where protection of the alcohol functionality is required. Its cyclobutanone core serves as a strained ring system useful in ring-expansion or fragmentation strategies. Widely utilized in medicinal chemistry for the synthesis of bioactive molecules where temporary protection of polar groups is needed to improve solubility or reactivity in non-aqueous environments.
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