1-Bromo-3-ethynyl-5-fluorobenzene
98%
Reagent
Code: #154866
CAS Number
1935278-77-5
blur_circular Chemical Specifications
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Molecular Information
Weight
199.02 g/mol
Formula
C₈H₄BrF
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Registry Numbers
MDL Number
MFCD31654732
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of fluorinated organic compounds. Its ethynyl and bromo functional groups allow for selective cross-coupling reactions, such as Sonogashira and Suzuki couplings, enabling the construction of complex aromatic systems. Commonly employed in medicinal chemistry for modifying bioactive molecules to enhance metabolic stability and binding affinity. Also utilized in materials science for creating conjugated organic frameworks and fluorescent probes due to its rigid aromatic structure and halogen substitution.
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1-Bromo-3-ethynyl-5-fluorobenzene
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of fluorinated organic compounds. Its ethynyl and bromo functional groups allow for selective cross-coupling reactions, such as Sonogashira and Suzuki couplings, enabling the construction of complex aromatic systems. Commonly employed in medicinal chemistry for modifying bioactive molecules to enhance metabolic stability and binding affinity. Also utilized in materials science for creating conjugated organic frameworks and fluorescent probes due to its rigid aromatic structure and halogen substitution.
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