4-((1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy)phthalonitrile
99%
Reagent
Code: #157496
CAS Number
906673-33-4
blur_circular Chemical Specifications
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Molecular Information
Weight
276.05 g/mol
Formula
C₁₅H₉BN₂O₃
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Registry Numbers
MDL Number
MFCD18633196
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Physical Properties
Boiling Point
495.6±55.0 °C(Predicted)
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Storage & Handling
Density
1.39±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of boron-containing pharmaceuticals and agrochemicals, particularly in the development of proteasome inhibitors for cancer therapy. Its boronic ester functionality enables selective binding to biological targets, enhancing drug efficacy. Also employed in materials science for creating luminescent sensors due to its ability to form stable complexes with diols and catechols, useful in detecting sugars and neurotransmitters. Commonly applied in Suzuki-Miyaura cross-coupling reactions to build complex aromatic structures in medicinal chemistry.
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4-((1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy)phthalonitrile
Used as a key intermediate in the synthesis of boron-containing pharmaceuticals and agrochemicals, particularly in the development of proteasome inhibitors for cancer therapy. Its boronic ester functionality enables selective binding to biological targets, enhancing drug efficacy. Also employed in materials science for creating luminescent sensors due to its ability to form stable complexes with diols and catechols, useful in detecting sugars and neurotransmitters. Commonly applied in Suzuki-Miyaura cross-coupling reactions to build complex aromatic structures in medicinal chemistry.
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