Cyclic Pifithrin-α Hydrobromide

≥98%

Reagent Code: #161186
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CAS Number 511296-88-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 349.29 g/mol
Formula C₁₆H₁₆N₂S·HBr
badge Registry Numbers
MDL Number MFCD02683960
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used primarily as a research compound in cellular and molecular biology, this chemical acts as a reversible inhibitor of p53, a tumor suppressor protein involved in cell cycle regulation and apoptosis. By temporarily suppressing p53 activity, it allows scientists to study the role of p53 in stress responses, DNA damage, and cell death pathways. It is particularly valuable in experiments where transient inhibition of p53 is needed to improve cell survival during stressful laboratory procedures such as cell culture, transfection, or cryopreservation. Its reversible nature makes it advantageous over permanent inhibitors, enabling restoration of normal p53 function after treatment. Commonly applied in studies related to cancer, neurodegeneration, and aging.

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Test Parameter Specification
Appearance White to Off-White Powder or Crystals
Purity (HPLC) 98.0-100%
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

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Size Availability Unit Price Quantity
inventory 20mg
10-20 days $225.04
inventory 100mg
10-20 days $456.55
inventory 250mg
10-20 days $682.45
Cyclic Pifithrin-α Hydrobromide
Used primarily as a research compound in cellular and molecular biology, this chemical acts as a reversible inhibitor of p53, a tumor suppressor protein involved in cell cycle regulation and apoptosis. By temporarily suppressing p53 activity, it allows scientists to study the role of p53 in stress responses, DNA damage, and cell death pathways. It is particularly valuable in experiments where transient inhibition of p53 is needed to improve cell survival during stressful laboratory procedures such as cell culture, transfection, or cryopreservation. Its reversible nature makes it advantageous over permanent inhibitors, enabling restoration of normal p53 function after treatment. Commonly applied in studies related to cancer, neurodegeneration, and aging.
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