4-(3-Carboxy-5-fluorophenyl)-2-fluorobenzoic acid

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Reagent Code: #166686
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CAS Number 1261978-52-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 278.21 g/mol
Formula C₁₄H₈F₂O₄
badge Registry Numbers
MDL Number MFCD18321471
thermostat Physical Properties
Boiling Point 492.8±45.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.478±0.06 g/cm3(Predicted)
Storage 2-8°C, sealed, dry

description Product Description

Used as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules. Its dual carboxylic acid functionality and fluorine substitution make it valuable for constructing complex aromatic frameworks with enhanced metabolic stability and binding affinity. Commonly employed in coupling reactions to form amide or ester linkages in drug candidates. Also utilized in the preparation of fluorinated ligands for medicinal chemistry research, where the fluorine atoms improve pharmacokinetic properties.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿29,540.00
4-(3-Carboxy-5-fluorophenyl)-2-fluorobenzoic acid
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules. Its dual carboxylic acid functionality and fluorine substitution make it valuable for constructing complex aromatic frameworks with enhanced metabolic stability and binding affinity. Commonly employed in coupling reactions to form amide or ester linkages in drug candidates. Also utilized in the preparation of fluorinated ligands for medicinal chemistry research, where the fluorine atoms improve pharmacokinetic properties.
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