4-(3-Carboxy-5-fluorophenyl)-2-fluorobenzoic acid
96%
Reagent
Code: #166686
CAS Number
1261978-52-2
blur_circular Chemical Specifications
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Molecular Information
Weight
278.21 g/mol
Formula
C₁₄H₈F₂O₄
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Registry Numbers
MDL Number
MFCD18321471
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Physical Properties
Boiling Point
492.8±45.0 °C(Predicted)
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Storage & Handling
Density
1.478±0.06 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules. Its dual carboxylic acid functionality and fluorine substitution make it valuable for constructing complex aromatic frameworks with enhanced metabolic stability and binding affinity. Commonly employed in coupling reactions to form amide or ester linkages in drug candidates. Also utilized in the preparation of fluorinated ligands for medicinal chemistry research, where the fluorine atoms improve pharmacokinetic properties.
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4-(3-Carboxy-5-fluorophenyl)-2-fluorobenzoic acid
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules. Its dual carboxylic acid functionality and fluorine substitution make it valuable for constructing complex aromatic frameworks with enhanced metabolic stability and binding affinity. Commonly employed in coupling reactions to form amide or ester linkages in drug candidates. Also utilized in the preparation of fluorinated ligands for medicinal chemistry research, where the fluorine atoms improve pharmacokinetic properties.
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