(6-Chloro-1-hexyn-1-yl)trimethylsilane
≥95%
Reagent
Code: #166713
CAS Number
113964-33-3
blur_circular Chemical Specifications
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Molecular Information
Weight
188.77 g/mol
Formula
C₉H₁₇ClSi
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Registry Numbers
MDL Number
MFCD20621621
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Storage & Handling
Storage
2-8°C, Sealed, Dry, Light-proof, Inert Gas
description Product Description
Used as a key intermediate in organic synthesis, particularly in the preparation of complex molecules requiring selective alkyne functionalization. Its trimethylsilyl group stabilizes the terminal alkyne, making it suitable for Sonogashira coupling reactions, which are widely employed in pharmaceutical and agrochemical industries to form carbon-carbon bonds. The chloroalkyne moiety allows further derivatization, enabling the construction of conjugated systems found in bioactive compounds and functional materials. Commonly applied in research settings for the synthesis of natural products and specialty chemicals where controlled reactivity and protection of the alkyne are essential.
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(6-Chloro-1-hexyn-1-yl)trimethylsilane
Used as a key intermediate in organic synthesis, particularly in the preparation of complex molecules requiring selective alkyne functionalization. Its trimethylsilyl group stabilizes the terminal alkyne, making it suitable for Sonogashira coupling reactions, which are widely employed in pharmaceutical and agrochemical industries to form carbon-carbon bonds. The chloroalkyne moiety allows further derivatization, enabling the construction of conjugated systems found in bioactive compounds and functional materials. Commonly applied in research settings for the synthesis of natural products and specialty chemicals where controlled reactivity and protection of the alkyne are essential.
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