3'-Chloro-4'-methyl-[1,1'-biphenyl]-2-carbonitrile

98%

Reagent Code: #166721
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CAS Number 442670-45-3

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scatter_plot Molecular Information
Weight 227.69 g/mol
Formula C₁₄H₁₀ClN
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MDL Number MFCD07779319
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry

description Product Description

Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related sartan-class medications. Its structure allows for effective coupling in biphenyl-based pharmaceuticals, enhancing binding affinity to the AT1 receptor. Commonly employed in API manufacturing due to its reactive nitrile group and halogenated aromatic ring, facilitating further functionalization through cross-coupling reactions. Also utilized in research for developing new cardiovascular therapeutics.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿14,400.00
3'-Chloro-4'-methyl-[1,1'-biphenyl]-2-carbonitrile
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related sartan-class medications. Its structure allows for effective coupling in biphenyl-based pharmaceuticals, enhancing binding affinity to the AT1 receptor. Commonly employed in API manufacturing due to its reactive nitrile group and halogenated aromatic ring, facilitating further functionalization through cross-coupling reactions. Also utilized in research for developing new cardiovascular therapeutics.
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