Dibenzo-18-crown-6 is widely used as a phase transfer catalyst, particularly in facilitating the solubilization and transport of metal ions, especially potassium, across nonpolar and polar phases. It is effective in organic synthesis where alkali metal ions act as catalysts or reagents, enhancing reaction rates and selectivity. The compound is also employed in ion-selective electrodes due to its high binding affinity for potassium ions, making it useful in analytical chemistry and environmental monitoring. Additionally, it finds application in the separation and extraction of metal ions in hydrometallurgy and nuclear waste treatment. Its complexation properties are utilized in the design of sensors and in supramolecular chemistry for constructing molecular assemblies.