2-(Diphenylphosphino)-N-((S)-((1S, 2S, 4S, 5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methyl)benzamide
98%
Reagent
Code: #177922
CAS Number
1630973-06-6
blur_circular Chemical Specifications
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Molecular Information
Weight
613.73 g/mol
Formula
C₃₉H₄₀N₃O₂P
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Storage & Handling
Storage
Room temperature, dry, light-proof
description Product Description
Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective hydrogenation reactions. It is particularly effective in the synthesis of chiral amines and amino acid derivatives, which are important intermediates in pharmaceutical manufacturing. Due to its rigid quinuclidine backbone and tunable phosphine moiety, it provides high enantioselectivity and catalytic efficiency when coordinated with transition metals such as rhodium or ruthenium. Its application is prominent in the production of active pharmaceutical ingredients (APIs) where control of stereochemistry is critical for biological activity. The compound enables greener processes by allowing lower catalyst loadings and milder reaction conditions.
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2-(Diphenylphosphino)-N-((S)-((1S, 2S, 4S, 5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methyl)benzamide
Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective hydrogenation reactions. It is particularly effective in the synthesis of chiral amines and amino acid derivatives, which are important intermediates in pharmaceutical manufacturing. Due to its rigid quinuclidine backbone and tunable phosphine moiety, it provides high enantioselectivity and catalytic efficiency when coordinated with transition metals such as rhodium or ruthenium. Its application is prominent in the production of active pharmaceutical ingredients (APIs) where control of stereochemistry is critical for biological activity. The compound enables greener processes by allowing lower catalyst loadings and milder reaction conditions.
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