(E)-Cyclooct-4-en-1-yl (2,5-dioxopyrrolidin-1-yl) carbonate
≥83%
Reagent
Code: #181032
CAS Number
1191901-33-3
blur_circular Chemical Specifications
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Molecular Information
Weight
267.28 g/mol
Formula
C₁₃H₁₇NO₅
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Registry Numbers
MDL Number
MFCD24386372
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Storage & Handling
Storage
-20°C, stored in inert gas, avoiding light
description Product Description
Used as an activated carbonate reagent in organic synthesis, particularly for the efficient coupling of carboxylic acids with amines to form amide bonds. It is especially valuable in peptide synthesis and the preparation of bioconjugates due to its ability to operate under mild conditions with high selectivity. The (E)-cyclooctenyl group can serve as a traceless or cleavable linker in solid-phase synthesis or targeted delivery systems. Its stability in various solvents and controlled reactivity make it suitable for use in multi-step synthetic sequences where orthogonal protection strategies are required.
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(E)-Cyclooct-4-en-1-yl (2,5-dioxopyrrolidin-1-yl) carbonate
Used as an activated carbonate reagent in organic synthesis, particularly for the efficient coupling of carboxylic acids with amines to form amide bonds. It is especially valuable in peptide synthesis and the preparation of bioconjugates due to its ability to operate under mild conditions with high selectivity. The (E)-cyclooctenyl group can serve as a traceless or cleavable linker in solid-phase synthesis or targeted delivery systems. Its stability in various solvents and controlled reactivity make it suitable for use in multi-step synthetic sequences where orthogonal protection strategies are required.
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