Ethyl 4-chloro-3-hydroxybutanoate

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Reagent Code: #184811
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CAS Number 10488-69-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 166.61 g/mol
Formula C₆H₁₁ClO₃
badge Registry Numbers
MDL Number MFCD09839767
thermostat Physical Properties
Melting Point 136 °C
Boiling Point 263.44ºC at 760 mmHg
inventory_2 Storage & Handling
Density 1.187 g/cm3
Storage Room temperature

description Product Description

Used as a key intermediate in the synthesis of statin-class cholesterol-lowering drugs, particularly in the production of atorvastatin and rosuvastin. Its chiral hydroxy ester structure allows for selective transformations in multi-step pharmaceutical syntheses. Commonly employed in asymmetric synthesis to introduce the hydroxybutanoate side chain with high enantiomeric purity. Also utilized in the preparation of beta-hydroxy esters for fine chemicals and active pharmaceutical ingredients (APIs). Its functional groups enable further modifications such as oxidation, reduction, and coupling reactions in drug development.

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Size Availability Unit Price Quantity
inventory 5g
10-20 days ฿910.00
Ethyl 4-chloro-3-hydroxybutanoate
Used as a key intermediate in the synthesis of statin-class cholesterol-lowering drugs, particularly in the production of atorvastatin and rosuvastin. Its chiral hydroxy ester structure allows for selective transformations in multi-step pharmaceutical syntheses. Commonly employed in asymmetric synthesis to introduce the hydroxybutanoate side chain with high enantiomeric purity. Also utilized in the preparation of beta-hydroxy esters for fine chemicals and active pharmaceutical ingredients (APIs). Its functional groups enable further modifications such as oxidation, reduction, and coupling reactions in drug development.
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