Ethyl 4-chloro-3-hydroxybutanoate
70%
Reagent
Code: #184811
CAS Number
10488-69-4
blur_circular Chemical Specifications
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Molecular Information
Weight
166.61 g/mol
Formula
C₆H₁₁ClO₃
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Registry Numbers
MDL Number
MFCD09839767
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Physical Properties
Melting Point
136 °C
Boiling Point
263.44ºC at 760 mmHg
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Storage & Handling
Density
1.187 g/cm3
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of statin-class cholesterol-lowering drugs, particularly in the production of atorvastatin and rosuvastin. Its chiral hydroxy ester structure allows for selective transformations in multi-step pharmaceutical syntheses. Commonly employed in asymmetric synthesis to introduce the hydroxybutanoate side chain with high enantiomeric purity. Also utilized in the preparation of beta-hydroxy esters for fine chemicals and active pharmaceutical ingredients (APIs). Its functional groups enable further modifications such as oxidation, reduction, and coupling reactions in drug development.
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Ethyl 4-chloro-3-hydroxybutanoate
Used as a key intermediate in the synthesis of statin-class cholesterol-lowering drugs, particularly in the production of atorvastatin and rosuvastin. Its chiral hydroxy ester structure allows for selective transformations in multi-step pharmaceutical syntheses. Commonly employed in asymmetric synthesis to introduce the hydroxybutanoate side chain with high enantiomeric purity. Also utilized in the preparation of beta-hydroxy esters for fine chemicals and active pharmaceutical ingredients (APIs). Its functional groups enable further modifications such as oxidation, reduction, and coupling reactions in drug development.
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