Ethyl 3-iodobicyclo[1.1.1]pentane-1-carboxylate
98%
- Product Code: 185193
CAS:
1936371-35-5
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| Density: | Storage Condition: | 2-8°C, drying away from light |
Product Description:
Used as a key intermediate in medicinal chemistry for the synthesis of bioisosteres, particularly in place of phenyl or tert-butyl groups to improve metabolic stability and solubility in drug candidates. Its strained bicyclic structure enables unique three-dimensional scaffolding, enhancing binding selectivity in pharmaceuticals. Commonly employed in fragment-based drug discovery and in the development of CNS-targeted compounds due to favorable physicochemical properties. Also utilized in cross-coupling reactions, such as Suzuki-Miyaura or Negishi couplings, to introduce the bicyclo[1.1.1]pentane moiety into complex molecules.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.050 G | 10-20 days | ฿5,080.00 |
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| 0.100 G | 10-20 days | ฿6,620.00 |
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| 0.250 G | 10-20 days | ฿12,260.00 |
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Ethyl 3-iodobicyclo[1.1.1]pentane-1-carboxylate
Used as a key intermediate in medicinal chemistry for the synthesis of bioisosteres, particularly in place of phenyl or tert-butyl groups to improve metabolic stability and solubility in drug candidates. Its strained bicyclic structure enables unique three-dimensional scaffolding, enhancing binding selectivity in pharmaceuticals. Commonly employed in fragment-based drug discovery and in the development of CNS-targeted compounds due to favorable physicochemical properties. Also utilized in cross-coupling reactions, such as Suzuki-Miyaura or Negishi couplings, to introduce the bicyclo[1.1.1]pentane moiety into complex molecules.
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