1-(4-Fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-1,2-dihydro-2-oxo-3-pyridinecarboxamide
98%
Reagent
Code: #186575
CAS Number
888719-03-7
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Molecular Information
Weight
458.42 g/mol
Formula
C₂₅H₁₆F₂N₄O₃
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Registry Numbers
MDL Number
MFCD16619360
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Physical Properties
Melting Point
212-214 °C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a potent inhibitor in pharmaceutical research, particularly targeting Janus kinase (JAK) enzymes. It shows promise in the development of treatments for autoimmune diseases such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease due to its ability to modulate immune signaling pathways. Its structure allows for high selectivity and improved pharmacokinetic properties, making it a valuable scaffold in optimizing JAK inhibitor candidates. Also investigated for potential use in oncology due to the role of JAK-STAT signaling in certain cancers.
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1-(4-Fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-1,2-dihydro-2-oxo-3-pyridinecarboxamide
Used as a potent inhibitor in pharmaceutical research, particularly targeting Janus kinase (JAK) enzymes. It shows promise in the development of treatments for autoimmune diseases such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease due to its ability to modulate immune signaling pathways. Its structure allows for high selectivity and improved pharmacokinetic properties, making it a valuable scaffold in optimizing JAK inhibitor candidates. Also investigated for potential use in oncology due to the role of JAK-STAT signaling in certain cancers.
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