1-(4-Fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-1,2-dihydro-2-oxo-3-pyridinecarboxamide

98%

  • Product Code: 186575
  CAS:    888719-03-7
Molecular Weight: 458.42 g./mol Molecular Formula: C₂₅H₁₆F₂N₄O₃
EC Number: MDL Number: MFCD16619360
Melting Point: 212-214 °C Boiling Point:
Density: Storage Condition: 2-8°C
Product Description: Used as a potent inhibitor in pharmaceutical research, particularly targeting Janus kinase (JAK) enzymes. It shows promise in the development of treatments for autoimmune diseases such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease due to its ability to modulate immune signaling pathways. Its structure allows for high selectivity and improved pharmacokinetic properties, making it a valuable scaffold in optimizing JAK inhibitor candidates. Also investigated for potential use in oncology due to the role of JAK-STAT signaling in certain cancers.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.005 10-20 days $408.43
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0.010 10-20 days $748.79
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0.025 10-20 days $1,191.26
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1-(4-Fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-1,2-dihydro-2-oxo-3-pyridinecarboxamide
Used as a potent inhibitor in pharmaceutical research, particularly targeting Janus kinase (JAK) enzymes. It shows promise in the development of treatments for autoimmune diseases such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease due to its ability to modulate immune signaling pathways. Its structure allows for high selectivity and improved pharmacokinetic properties, making it a valuable scaffold in optimizing JAK inhibitor candidates. Also investigated for potential use in oncology due to the role of JAK-STAT signaling in certain cancers.
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