4'-Fluoro-3'-(trifluoromethyl)acetophenone
97%
Reagent
Code: #187218
Alias
5-acetyl-2-fluorobenzotrifluoride
CAS Number
208173-24-4
blur_circular Chemical Specifications
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Molecular Information
Weight
206.14 g/mol
Formula
C₉H₆F₄O
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Registry Numbers
MDL Number
MFCD00061252
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated active pharmaceutical ingredients (APIs) where the fluorine and trifluoromethyl groups enhance metabolic stability and binding affinity. Commonly employed in the production of anti-inflammatory, antiviral, and central nervous system agents. Its structure supports improved lipophilicity and bioavailability in drug candidates. Also utilized in agrochemicals for creating herbicides and pesticides with increased environmental persistence and efficacy. Frequently selected in medicinal chemistry for structure-activity relationship (SAR) studies due to its electron-withdrawing properties and ability to influence molecular conformation.
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4'-Fluoro-3'-(trifluoromethyl)acetophenone
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated active pharmaceutical ingredients (APIs) where the fluorine and trifluoromethyl groups enhance metabolic stability and binding affinity. Commonly employed in the production of anti-inflammatory, antiviral, and central nervous system agents. Its structure supports improved lipophilicity and bioavailability in drug candidates. Also utilized in agrochemicals for creating herbicides and pesticides with increased environmental persistence and efficacy. Frequently selected in medicinal chemistry for structure-activity relationship (SAR) studies due to its electron-withdrawing properties and ability to influence molecular conformation.
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