2-Fluoro-4-Methylanisole
≥97%
Reagent
Code: #187878
CAS Number
399-55-3
blur_circular Chemical Specifications
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Molecular Information
Weight
140.15 g/mol
Formula
C₈H₉FO
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Registry Numbers
MDL Number
MFCD00060270
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Physical Properties
Boiling Point
72 °C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where fluorinated aromatic compounds enhance metabolic stability and bioavailability. It serves as a building block in agrochemicals for creating herbicides and fungicides due to the electron-withdrawing effect of the fluorine atom combined with the methoxy group’s directing influence in electrophilic substitution reactions. Also employed in the preparation of liquid crystals and organic semiconductors, where the fluorine substitution helps fine-tune electronic properties and molecular packing behavior. Its selective reactivity makes it valuable in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig aminations, for constructing complex molecules in research and industrial settings.
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2-Fluoro-4-Methylanisole
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where fluorinated aromatic compounds enhance metabolic stability and bioavailability. It serves as a building block in agrochemicals for creating herbicides and fungicides due to the electron-withdrawing effect of the fluorine atom combined with the methoxy group’s directing influence in electrophilic substitution reactions. Also employed in the preparation of liquid crystals and organic semiconductors, where the fluorine substitution helps fine-tune electronic properties and molecular packing behavior. Its selective reactivity makes it valuable in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig aminations, for constructing complex molecules in research and industrial settings.
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