8-Fluoro-1H-quinazolin-4-one
95%
Reagent
Code: #188559
CAS Number
187805-50-1
blur_circular Chemical Specifications
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Molecular Information
Weight
164.14 g/mol
Formula
C₈H₅FN₂O
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Registry Numbers
MDL Number
MFCD09954860
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of fluorinated quinazoline derivatives, which show significant biological activity. Commonly applied in pharmaceutical research for developing anticancer agents, particularly as inhibitors of tyrosine kinases involved in tumor growth. Also explored in the design of anti-inflammatory and antimicrobial compounds due to its ability to modulate enzyme activity and interact with biological targets. Its fluorine substitution enhances metabolic stability and binding affinity, making it valuable in medicinal chemistry for structure-activity relationship studies.
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8-Fluoro-1H-quinazolin-4-one
Used as a key intermediate in the synthesis of fluorinated quinazoline derivatives, which show significant biological activity. Commonly applied in pharmaceutical research for developing anticancer agents, particularly as inhibitors of tyrosine kinases involved in tumor growth. Also explored in the design of anti-inflammatory and antimicrobial compounds due to its ability to modulate enzyme activity and interact with biological targets. Its fluorine substitution enhances metabolic stability and binding affinity, making it valuable in medicinal chemistry for structure-activity relationship studies.
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