(2-(((5-((4-Fluorophenyl)carbamoyl)pyrimidin-2-yl)thio)methyl)-4-(trifluoromethoxy)phenyl)boronic acid

≥98%

Reagent Code: #189486
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CAS Number 1648843-04-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 467.20 g/mol
Formula C₁₉H₁₄BF₄N₃O₄S
badge Registry Numbers
MDL Number MFCD28502254
inventory_2 Storage & Handling
Density 1.53±0.1 g/cm3(Predicted)
Storage 2-8°C, sealed, dry, inert gas

description Product Description

Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly for targeted cancer therapies. Its boronic acid functional group enables Suzuki-Miyaura cross-coupling reactions, facilitating the construction of complex biaryl structures found in bioactive molecules. Commonly employed in the development of tyrosine kinase and BTK inhibitors due to its ability to enhance binding affinity and selectivity. Also utilized in medicinal chemistry for optimizing pharmacokinetic properties such as metabolic stability and membrane permeability.

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Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿9,400.00
inventory 50mg
10-20 days ฿16,890.00
inventory 100mg
10-20 days ฿31,630.00
(2-(((5-((4-Fluorophenyl)carbamoyl)pyrimidin-2-yl)thio)methyl)-4-(trifluoromethoxy)phenyl)boronic acid
Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly for targeted cancer therapies. Its boronic acid functional group enables Suzuki-Miyaura cross-coupling reactions, facilitating the construction of complex biaryl structures found in bioactive molecules. Commonly employed in the development of tyrosine kinase and BTK inhibitors due to its ability to enhance binding affinity and selectivity. Also utilized in medicinal chemistry for optimizing pharmacokinetic properties such as metabolic stability and membrane permeability.
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