4-chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine
≥95%
Reagent
Code: #193847
CAS Number
651744-48-8
blur_circular Chemical Specifications
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Molecular Information
Weight
308.93 g/mol
Formula
C₁₆H₂₅ClN₂Si
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Registry Numbers
MDL Number
MFCD09763673
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Physical Properties
Boiling Point
320.5±35.0 °C(Predicted)
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Storage & Handling
Density
1.05±0.1 g/cm3(Predicted)
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows selective modification to enhance drug potency and bioavailability. Commonly employed in cross-coupling reactions due to the presence of the chloro group, enabling the formation of carbon-carbon and carbon-heteroatom bonds. The triisopropylsilyl protecting group ensures stability during multi-step syntheses and can be selectively removed under mild conditions, making it valuable in complex molecule assembly.
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4-chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows selective modification to enhance drug potency and bioavailability. Commonly employed in cross-coupling reactions due to the presence of the chloro group, enabling the formation of carbon-carbon and carbon-heteroatom bonds. The triisopropylsilyl protecting group ensures stability during multi-step syntheses and can be selectively removed under mild conditions, making it valuable in complex molecule assembly.
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