4-chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine

≥95%

Reagent Code: #193847
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CAS Number 651744-48-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 308.93 g/mol
Formula C₁₆H₂₅ClN₂Si
badge Registry Numbers
MDL Number MFCD09763673
thermostat Physical Properties
Boiling Point 320.5±35.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.05±0.1 g/cm3(Predicted)
Storage Room temperature

description Product Description

Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows selective modification to enhance drug potency and bioavailability. Commonly employed in cross-coupling reactions due to the presence of the chloro group, enabling the formation of carbon-carbon and carbon-heteroatom bonds. The triisopropylsilyl protecting group ensures stability during multi-step syntheses and can be selectively removed under mild conditions, making it valuable in complex molecule assembly.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿1,040.00
inventory 1g
10-20 days ฿2,530.00
inventory 25g
10-20 days ฿38,790.00
inventory 100mg
10-20 days ฿620.00
inventory 5g
10-20 days ฿9,210.00
4-chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows selective modification to enhance drug potency and bioavailability. Commonly employed in cross-coupling reactions due to the presence of the chloro group, enabling the formation of carbon-carbon and carbon-heteroatom bonds. The triisopropylsilyl protecting group ensures stability during multi-step syntheses and can be selectively removed under mild conditions, making it valuable in complex molecule assembly.
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