4-Hydroxy-6-(trifluoromethyl)pyrimidine

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Reagent Code: #194568
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CAS Number 1546-78-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 164.09 g/mol
Formula C₅H₃F₃N₂O
thermostat Physical Properties
Melting Point 169-171°C
Boiling Point 229°C
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its structure supports binding to enzyme active sites, enhancing selectivity and potency. Also employed in agrochemicals to improve metabolic stability and bioavailability in crop protection agents. The trifluoromethyl group contributes to lipophilicity and resistance to oxidative degradation, making it valuable in designing compounds with improved pharmacokinetic profiles.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 10g
10-20 days ฿1,780.00
inventory 25g
10-20 days ฿4,280.00
inventory 100g
10-20 days ฿15,200.00
4-Hydroxy-6-(trifluoromethyl)pyrimidine
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its structure supports binding to enzyme active sites, enhancing selectivity and potency. Also employed in agrochemicals to improve metabolic stability and bioavailability in crop protection agents. The trifluoromethyl group contributes to lipophilicity and resistance to oxidative degradation, making it valuable in designing compounds with improved pharmacokinetic profiles.
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