9-Hydroxy-α-lapachone

96%

Reagent Code: #195386
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CAS Number 22333-58-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 258.269 g/mol
Formula C₁₅H₁₄O₄
thermostat Physical Properties
Boiling Point 436.4±45.0℃ at 760 mmHg
inventory_2 Storage & Handling
Density 1.4±0.1g/ml
Storage 2-8℃, dry, sealed

description Product Description

Used in cancer research due to its ability to induce apoptosis in tumor cells through the generation of reactive oxygen species. It acts as a substrate for NQO1 (NAD(P)H:quinone oxidoreductase), an enzyme overexpressed in many cancer types, making it a candidate for targeted cancer therapy. Shows activity against lung, pancreatic, and breast cancer cells in preclinical studies. Also investigated for antiparasitic properties, particularly against Leishmania and Trypanosoma species. Its poor solubility and toxicity profile have led to development of drug delivery systems like nanoparticles and liposomes to improve bioavailability and reduce side effects.

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Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿51,610.00
9-Hydroxy-α-lapachone
Used in cancer research due to its ability to induce apoptosis in tumor cells through the generation of reactive oxygen species. It acts as a substrate for NQO1 (NAD(P)H:quinone oxidoreductase), an enzyme overexpressed in many cancer types, making it a candidate for targeted cancer therapy. Shows activity against lung, pancreatic, and breast cancer cells in preclinical studies. Also investigated for antiparasitic properties, particularly against Leishmania and Trypanosoma species. Its poor solubility and toxicity profile have led to development of drug delivery systems like nanoparticles and liposomes to improve bioavailability and reduce side effects.
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