8-Hydroxydigitoxigenin
95%
Reagent
Code: #195509
CAS Number
1049674-06-7
blur_circular Chemical Specifications
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Molecular Information
Weight
390.51 g/mol
Formula
C₂₃H₃₄O₅
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Registry Numbers
MDL Number
MFCD20274985
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Storage & Handling
Storage
2-8℃, dry, closed
description Product Description
Used in the synthesis of cardiotonic drugs, particularly in the development of cardiac glycosides that enhance heart contraction. It serves as an intermediate in modifying steroid structures to improve pharmacological activity and selectivity for treating heart failure and certain arrhythmias. Its hydroxyl group at position 8 allows for chemical derivatization, enabling optimization of solubility and binding affinity to the Na⁺/K⁺-ATPase enzyme in cardiac tissue.
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8-Hydroxydigitoxigenin
Used in the synthesis of cardiotonic drugs, particularly in the development of cardiac glycosides that enhance heart contraction. It serves as an intermediate in modifying steroid structures to improve pharmacological activity and selectivity for treating heart failure and certain arrhythmias. Its hydroxyl group at position 8 allows for chemical derivatization, enabling optimization of solubility and binding affinity to the Na⁺/K⁺-ATPase enzyme in cardiac tissue.
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